Elizabeth C. Watters Research Fellowship

Deadline: Likely July 2021

A fellowship has been made available through an endowment established by the Estate of John Imrie Watters for a deserving graduate student or medical resident in the Faculty of Medicine engaged in research into the causes, treatment, and cure of lymphatic cancer. Mr. Watters passed away in 2002. The awards are made on the recommendation of the Faculty of Medicine, and in the case of graduate students, in consultation with the Faculty of Graduate and Postdoctoral Studies.

Award

$20,600 for one year.

Eligibility

Applicants must be registered as full-time graduate students or medical residents in the Faculty of Medicine. Applicants must be in good academic standing, and conducting research under the supervision of a UBC faculty member who has a primary appointment in the Faculty of Medicine. Applicants who already hold a major award at the time of the award conferral will not be eligible to receive payment of the award and will be recognized in name only if successful.

Application Procedure

A completed application consists of:

1. Application for the Fellowship
a.) Complete, sign and scan the Application Form in either PDF or Word formats.
b.) Submit the Application Form via the Online Portal.

2. Post-secondary transcripts from all post-secondary institutions attended
Electronic copies of transcripts must be submitted, and do not require initialing, but must be shared with the GPE Office via OneDrive by the graduate program assistant.

3. Letters of support from two sponsors
One letter should be from the proposed or current supervisor of the candidate, and the other from an individual familiar with the candidate’s academic and research abilities. Sponsors should be asked to comment on the candidate’s research potential and achievements, interpersonal skills, academic abilities, and greatest strengths and weaknesses. Electronic copies of letters of support are accepted if sent directly from the sponsor. To facilitate a blind review process, please ask your supervisor to not use your name, gender specific pronouns, or similar identifying characteristics in their letters. They should refer to you as “The Trainee” as needed. 

Complete applications need to be received by: TBA

Transcripts and letters of support should be submitted to:
med.research@ubc.ca

Please refer to the Guidelines and FAQs for specific formatting and submission details.

Elizabeth C. Watters Research Fellowship Recipients

Brett Collinge is an MSc Candidate in the Pathology and Laboratory Medicine Program and is conducting his research at the BC Cancer Research Institute under the supervision of Dr. David Scott. His research focuses on understanding the underlying mechanisms that drive the aggressive disease course of the most difficult-to-treat lymphomas, with the aim of identifying the key features that distinguish these lymphomas from others with more favorable outcomes. Efforts to address the disparity in outcomes among different lymphomas have primarily focused on intensifying chemotherapy regimens. This approach has yielded limited success, highlighting the need for the development of new treatment strategies. A promising approach to addressing this clinical challenge is “precision medicine”, where patients receive treatment that is specifically tailored to the features unique to their individual cancer. However, the key genetic features that characterize the most difficult-to-treat subset of aggressive lymphomas remain unknown. Through identifying these features, Brett’s research aims to guide the development of new treatment strategies that will ultimately improve the outcomes of patients with the most clinically challenging lymphomas.

Yu (Michael) Li is a PhD Candidate in the Pathology and Laboratory Medicine program and researches lymphoma, the most common group of blood cancers in Canada, under the supervision of Dr. Christian Steidl. Despite recent advances in early diagnosis and treatment of these diseases, a third of lymphoma patients do not respond effectively to treatment or redevelop more severe ailment after first-round therapy. The underlying causes of treatment failure are not fully understood, but several studies have suggested potential explanations including: (1) DNA mutations which affect the expression of survival-associated genes in cancer cells, and (2) changes in cell-to-cell interactions which affect the behaviour of both cancer cells and surrounding cells in the tumour microenvironment. The focus of Michael’s dissertation project is to improve our understanding of the role of recurrent TRAF3 mutations in B cell lymphomas, research that may aid in identifying rational therapeutic targets and alternative treatment for people living with these diseases.

Annie Tam is a PhD Candidate in the Medical Genetics Program and researches leukemia, the cancer of blood cells, under the supervision of Dr. Peter Stirling. Myelodysplastic syndromes (MDS) are a group of disorders that affect every blood cell type, and often transform into acute myeloid leukemia (AML), the most common type of acute leukemia in adults. Most MDS patients have been identified as having a mutation in their RNA splicing factors. Although the mutation in a specific RNA splicing factor named SF3B1 is commonly observed, the specifics of how it contributes to disease progression remain unknown, and provides the focus to Annie’s dissertation project.